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  ["title"] => string(92) "Everything You Need To Know About Nucleic Acid Extractors: What, How, Applications, and More"
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  ["content"] => string(7151) "<p>While the original nucleic acid extraction method was first introduced in 1869[1], many new advancements and discoveries have been made. Today, nucleic acid extractors play a significant role in genomic studies and the diagnostics process of certain illnesses. Different techniques are used for this procedure, but a high-quality extractor forms a strong foundation.<br/></p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230614/1686723245811192.png" title="" alt="a.png"/></p><p><em>Image 1: A diagram showing the structure of RNA (left) and DNA (right). Uracil is the base paired with adenine in RNA, whereas thymine is paired with adenine in DNA. Image credit: Wikipedia</em></p><p><br/></p><p><strong>What is Nucleic Acid Extractor</strong></p><p>Nucleic acid extraction is the initial step in the NGS sample preparation protocol. Nucleic acids are large biological molecules essential to all known forms of life. They consist of nucleotides, monomers composed of three components - sugars, phosphates, and nitrogenous bases. The two major classes of nucleic acids are DNA and RNA. The sugar of RNA is ribose, while the sugar of DNA is deoxyribose.</p><p><br/></p><p><strong>The Workflow of the Nucleic Acid Extractor Device</strong></p><p>Nucleic acid extraction is always the first step in any nucleic acid-related experiment. It is a critical pre-analytical step in the development and execution of any successful molecular diagnostic method to ensure reliable results. Nucleic acid extraction consists of three main processes: isolation, purification, and concentration.</p><p>The workflow of a nucleic acid extraction machine device generally involves several common steps. Here is a general outline of the workflow:</p><p><strong>1.	Sample Preparation:</strong> Collect the biological sample (e.g., blood, tissue, swab) containing the nucleic acids of interest.&nbsp;</p><p><strong>2.	Lysis:</strong> The sample is treated with a lysis buffer or reagent to break down cell membranes and release the nucleic acids. This step aims to disrupt cellular structures and make the nucleic acids accessible for extraction.</p><p><strong>3.	Binding:</strong> After release, the nucleic acids are attached to a solid support or matrix, like magnetic beads or a silica membrane. The solid support holds onto the nucleic acids while removing any other contaminants through washing.</p><p><strong>4.	Washing: </strong>The bound nucleic acids are washed to remove impurities, including proteins, lipids, and other cellular components.&nbsp;</p><p><strong>5.	Elution: </strong>The purified nucleic acids are eluted or released from the solid support, typically using a low-salt or nuclease-free buffer.&nbsp;</p><p><strong>6.	Quantification and Quality Control: </strong>The extracted nucleic acids are often quantified using spectrophotometry or fluorometric methods to determine their concentration.&nbsp;</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230614/1686723321413028.png" title="" alt="b.png"/></p><p><strong>Applications of Nucleic Acid Extraction Techniques</strong></p><p>A nucleic acid extractor can be used in a variety of settings. It&#39;s an in vitro diagnostic medical device and an option that can be used in food, forensics, and more. Let&#39;s take a closer look at the potential applications of a nucleic acid extraction machine:</p><p><strong>1.	Healthcare: </strong>In healthcare, a nucleic acid extractor can be used to extract both RNA and DNA from blood, tissue, and saliva. This can be used to test for genetic disorders. Certain infectious diseases can also be identified.&nbsp;</p><p><strong>2.	Biodiversity Assessment: </strong>With the suitable extraction method, it&#39;s possible to use a nucleic acid extractor to determine the bacteria, viruses, fungi, and other microorganisms that are present in a specific environment.&nbsp;</p><p><strong>3.	Food and Pharmaceutical Industries: </strong>With a nucleic acid extractor, it&#39;s possible to test food samples, as well as pharmaceutical products, to try for their safety. The method can be used to determine if certain species of harmful bacteria are present in food, for example.&nbsp;</p><p><strong>4.	Forensics: </strong>These techniques are also valuable for forensics, as they can help detect the cause of death and identify individuals.&nbsp;</p><p><strong>5.	CDC:</strong> In cities and country-wide applications, a nucleic acid extractor becomes a helpful tool in detecting the spread of an infectious disease or understanding where an outbreak is coming from.&nbsp;</p><p><br/></p><p><strong>Game-Changer: Tianlong&#39;s GeneRotex 96 Nucleic Acid Extractor</strong></p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230614/1686723391289117.png" title="" alt="c.png"/></p><p>Tianlong GeneRotex 96 Nucleic Acid Extractor is based on the automatic extraction principle of magnetic bead adsorption separation. Using magnetic microspheres as the carrier for nucleic acid separation and purification can overcome the shortcomings of traditional extraction methods of complicated steps, time-consuming, low yield, and challenging to achieve automatic operation, thus realizing rapid and efficient preparation of samples. Here are some key features of GeneRotex 96 Nucleic Acid Extraction Machine:</p><p><strong>Flexible: </strong>With the GeneRotex96, you can flexibly and efficiently extract 1 to 96 samples in each run. Also, there is the flexibility to create, edit and delete protocols.</p><p><strong>Efficient:</strong> The innovative 6*16 extraction module, compatible with 96-well deep-well plates and 6-tube strips, provides high-throughput extraction with less reagent waste without the inconvenience of traditional throughput fixation. This unit also includes an automatic control system with motor-driven automatic opening and closing of the lab cabinet, making it faster and more efficient.</p><p><strong>Safe and Accurate: </strong>The Tianlong GeneRotex 96 Nucleic Acid Extractor is designed with our innovative Rotational Mixing Technology (RMT), which reduces aerosol generation during purification, minimizes the risk of false positives due to cross-contamination, and ensures the accuracy of experimental results.</p><p><strong>Accessibility: </strong>It is equipped with a 7-inch color touch screen, simple and easy to understand, and convenient for experimental personnel to operate.</p><p><br/></p><p><strong>Conclusion</strong></p><p>Tianlong holds 120 international certificates, and its selection of laboratory equipment reaches labs in over 100 countries. The company has over 80 intellectual property rights, with 70 NMPA approvals. Our company offers various laboratory equipment, including PCR thermal cyclers, PCR systems, and nucleic acid extractor options. Find out how TianLong can help your lab grow and improve performance by contacting us.&nbsp;</p><p><br/></p><p>References</p><p>[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529626/</p>"
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  ["title"] => string(74) "Tianlong will be attending the 48th Brazilian Society of Clinical Analysis"
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  ["content"] => string(2391) "<p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230613/1686645973328269.png" title="" alt="bb.png"/></p><p>We are pleased to announce Tianlong’s presence at the 48th Brazilian Society of Clinical Analysis, which presents a great opportunity for Tianlong to share our wealth of products and innovative technologies with the industry.&nbsp;</p><p><strong>Brazilian Society of Clinical Analysis</strong></p><p style="text-align: center;"><strong><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230613/1686645947792572.png" title="" alt="aa.png"/></strong></p><p>DATES: 18 June – 21 June 2023<br/></p><p>LOCATION: Costao do Santinho Resort, Florianopolis, Brazil</p><p>BOOTH:&nbsp;69A+69B</p><p><br/></p><p>Tianlong will be attending this event with our all-in-one molecular diagnosis system Panall 8000, our latest offering for PCR laboratory diagnostics.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230613/1686646019630645.png" title="" alt="cc.png"/></p><p>Tianlong&#39;s newly launched Panall 8000 All-in-one Molecular Diagnosis System includes its self-developed full-automatic nucleic acid detection analysis system and a number of multi-pathogen nucleic acid detection kits. Based on the principle of Magnetic Beads method and real-time PCR reaction, Panall 8000 can be matched with compatible reagents for sample nucleic acid extraction, in vitro nucleic acid amplification and analysis in molecular detection. It is a simple and secure molecular diagnosis system that integrates the functions of sample tube decapping/capping, sample loading, nucleic acid extraction, PCR setup, PCR detection and result analysis, and can detect up to 24 target genes in a single sample with one reagent, which can realize a true “sample in -result out” detection process and bring great convenience for professionals with only one-key operation.</p><p>Panall 8000 can be widely used in community hospital, hospital emergency, CDC and research institute. With the compatible reagents, Panall 8000 can run parallel detections, including pathogen detections in respiratory disease, sexual transmitted disease, gastroenteric diseases, etc., to provide an overall solution for early and accurate identification of pathogenic microorganisms</p>"
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  ["content"] => string(1069) "<p>On the World Food Safety Day 2023, Tianlong safeguards the food safety with its Biolum Portable ATP Hygiene Monitoring System.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230607/1686127022108976.png" title="" alt="700x400.png"/></p><p>Biolum Portable ATP Hygiene Monitoring System is a powerful tool for implementing and managing your hygiene monitoring program. Taking advantage of the progressive testing swab, the hygiene level will be evaluated in seconds, and the results can be visualized on screen. Featuring state-of-art technology, the Biolum is a user-friendly, flexible, and accurate quality monitoring system. It has all the features to maximize its value to your business.</p><p>Tianlong’s Biolum Portable ATP Hygiene Monitoring System has assisted in the food safety monitoring and hygiene assurance of many major events including the National Games, G20 Summit, and Davos Forum, and has multiple applications in environmental protection, food service, and healthcare industries.</p>"
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  ["content"] => string(6017) "<p><strong>Introduction</strong><br/></p><p>What is a molecular diagnostics system? It sounds like fancy yet unfamiliar equipment to many of us. In actuality, molecular diagnosis systems are medical diagnostic tools that use molecular techniques to detect the presence or absence of specific DNA, RNA, or protein sequences in a biological sample, such as blood, urine, or tissue. In such a way, molecular diagnostic systems identify the genetic basis of a disease, detect pathogens such as bacteria or viruses, and monitor the effectiveness of treatment.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230602/1685697420437484.png" title="" alt="aa.png"/></p><p>Efficiency is the merit of molecular diagnosis systems. Contrary to the traditional approach, where medical testing was restricted to a complicated and lengthy procedure, and patients had to endure long waiting periods of several hours, or even days, to receive the test results, molecular diagnosis systems provide quick results. This allows patients to receive prompt treatment and management without any delay caused by the lack of information. Moreover, molecular diagnosis systems also offer the convenience of testing specimens outside the clinical laboratory setting, making it possible to perform tests in different locations where traditional diagnostic tools are unavailable.</p><p>There are numerous types of molecular diagnostic systems available, some capable of performing polymerase chain reaction (PCR) and nucleic acid extraction, while others are good for data analysis through the molecular diagnosis kit. With these remarkable techniques, even with very small amounts of genetic material, the detection result can still remain highly sensitive and specific.</p><p>In this article, let us have a close look at the applications, benefits, and key features of Panall 8000, a new member of Panall’s All-in-one Molecular Diagnosis System series, as well as the fast track to a faster and more accurate diagnosis of diseases.&nbsp;</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230602/1685697444844803.png" title="" alt="bb.png"/></p><p><strong>Application in Different Scenarios</strong><br/></p><p>As stated earlier, the molecular diagnostic system is suitable for use in various settings, including clinical and non-clinical ones. The clinical settings where it can be used include biological and clinical emergencies, military safety, and health management. On the other hand, the non-clinical settings include a broader range of places, such as remote areas, customs, airports, clinics, and emergency rooms. As these places often experience a high volume of people gathering or traveling daily, emergency care and a molecular diagnostic workstation are necessary.</p><p><strong>Key Strengths and Features</strong></p><p>The Tianlong Panall 8000 All-in-one Molecular Diagnosis System is an easy-to-operate and safe molecular test tool that combines several functions into one device. These functions include sample tube decapping/capping, sample loading, nucleic acid extraction, PCR setup, PCR detection, and result analysis. This system enables a seamless detection process from sample to result, making it very convenient for professionals with a simple one-key operation.</p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230602/1685697472943730.png" title="" alt="cc.png"/></p><p>Panall 8000 covers a wide range of diseases in its test menu. This molecular diagnosis system is well capable of rapidly diagnosing pathogens associated with different respiratory infectious diseases, including 7 types of respiratory pathogens (Flu A, Flu B, RSV, ADV, HRV, HPIV and MP), respiratory 17 types of pathogens (Flu A, Flu A/H1, Flu A/H3, Flu B, RSV, ADV, HRV, HPIV1, HPIV2/4, HPIV3, CP, MP, CorHKU1/OC43, CorNL63/229, HMPV, HBoV and SARS-COV-2), and more in the coming days! Therefore, this molecular diagnosis system does not just enable timely and accurate diagnosis in all scenarios for efficient detection and rapid treatment, but also contribute greatly to the control of infectious diseases.&nbsp;</p><p>But being good at detecting so many diseases is merely a start! Panall 8000 also has the following features that make it state-of-the-art:&nbsp;</p><p>1. This in vitro diagnostic medical device provides a seamless detection process from sample to result.</p><p>2. The model is designed to minimize contamination through its closed design.</p><p>3. Featuring a 12.1-inch touchscreen, the molecular diagnosis system is safely user-friendly and easy to navigate.</p><p>4. Panall 8000 does not require any additional equipment to operate.</p><p>5. The molecular diagnosis system provides results that are easy to interpret without the need for any further analysis.</p><p>6. The model is capable of testing up to 8 samples simultaneously.</p><p>7. The system offers reliable and high-quality results that users can depend on.</p><p><strong>Conclusion&nbsp;</strong></p><p>As the top-of-the-line instrument manufacturers, Tianlong Science and Technology has been making an unremitting effort to integrate PCR lab solution to the research, development and production of PCR lab instruments and reagent kits in molecular diagnostics.&nbsp;</p><p>For the past 2 decades, Tianlong has been engaged in the research and development of a set of products, ranging from viral transportation medium, sample processing system, nucleic acid extractor, nucleic acid extraction kit, real-time PCR system, PCR test kit, liquid handling system to ATP hygiene monitor, etc., dedicated to providing professional and integrated PCR lab solution in molecular diagnosis ever since its establishment, and will continue to develop the top reagents and instruments for the well-being of all humanity.&nbsp;</p><p>Partner up with Tianlong and stay safe and healthy!</p>"
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  ["title"] => string(56) "A Guide for New Mothers: The Necessity of Gene Detection"
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  ["content"] => string(6997) "<p>The month of May provides us with the unique opportunity to honor the incredible women who have embarked on the beautiful journey of motherhood. Amidst the heartwarming celebrations, it is essential to note the continually changing landscape of maternal care and the importance of gene detection in ensuring the well-being of both mother and child.&nbsp;<br/></p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230602/1685697013280713.png" title="" alt="1.png"/></p><p>American doctors recently found that more than 70% of women opt to undergo genetic screening during their prenatal appointments. With such an increased statistic, this article investigates the necessity of genetic tests for new mothers.&nbsp;</p><p><strong>The Importance of Gene Detection</strong></p><p>The introduction of genetic tests has significantly impacted obstetrics, allowing healthcare providers to detect genetic abnormalities during early pregnancy.</p><p>Gene detection, a rapidly advancing field in healthcare, has revolutionized how expectant mothers and newborns are cared for. By uncovering valuable genetic information, these tests offer vital insights into potential risks, enabling proactive measures to be taken for the well-being of both mother and child.&nbsp;</p><p>The necessity of gene detection in these genetic tests cannot be overstated. By harnessing the power of genetic tests, healthcare professionals can identify potential risks, create personalized care plans, and guide expectant mothers through informed decision-making processes. By understanding these risks beforehand, mothers can collaborate with medical&nbsp;</p><p><strong>Two Significant Gene Detections for New Mothers and Newborns</strong></p><p>Having advanced knowledge is crucial to ensure the health and well-being of expectant mothers and newborns. Two genetic testing tests can provide this essential information for better outcomes.</p><p><strong>The Group B strep test for expectant mothers</strong></p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230602/1685697063868795.jpg" title="" alt="2.jpg"/></p><p>Group B Streptococcus (GBS) is a common bacterium that can be present in the genital or gastrointestinal tracts of expectant mothers. While GBS is usually harmless in adults, it can pose severe risks to newborns if transmitted during childbirth. Neonatal sepsis, meningitis, and pneumonia can be caused by Group B streptococcal infection, which has a very high mortality rate. It is currently considered one of the most significant pathogens responsible for neonatal infections.</p><p>The GBS test involves a simple swab of the vagina and rectum, which is then analyzed for the presence of GBS bacteria. If positive, healthcare professionals will take the necessary precautions to significantly reduce the risk of transmitting GBS to the newborn.&nbsp;</p><p><strong>The Spinal Muscular Atrophy (SMA) test for newborns</strong></p><p style="text-align: center;"><img class="new_ueditor_box_img" src="/Public/Uploads/ueditor/upload/image/20230602/1685697089420660.jpg" title="" alt="3.jpg"/></p><p>The introduction of genetic tests has significantly impacted obstetrics, allowing healthcare providers to detect genetic abnormalities during early pregnancy.</p><p>SMA genetic testing is one of the primary genetic tests recommended for newborns. Spinal Muscular Atrophy (SMA) is a rare genetic disorder affecting motor neurons, leading to muscle weakness and potential disability. Early diagnosis is crucial, and SMA genetic testing identifies carriers of the gene mutation responsible and provides vital information that helps healthcare providers assess the risk and take necessary precautions to support the baby&#39;s well-being.&nbsp;</p><p>The SMA test, often performed alongside routine newborn screening, involves analyzing a blood sample to detect the presence of the SMN1 gene. The production of a necessary protein for motor neuron function depends on this particular gene. In addition, healthcare professionals can diagnose and intervene promptly by identifying this absence or mutation.&nbsp;</p><p><strong>The Advantages of Tianlong&#39;s Gene Detection Kits</strong></p><p>In genetic testing, accuracy, efficiency, and user-friendliness are paramount. Recognizing the growing demand for reliable diagnostic tools, Tianlong launched two cutting-edge products; the Group B Streptococcus (GBS) PCR Detection Kit and the Human Survival Motor Neuron 1 (SMN1) genetic test Kit-P124H. And here&#39;s why every expectant mother would find these kits extra useful.</p><p><strong>1. Accurate performance and Optimized workflow</strong></p><p>Tianlong&#39;s gene detection and gene testing kits have been meticulously designed to deliver precise, reliable results. Through advanced PCR technology, these kits ensure the accurate detection of specific genetic markers, enabling healthcare professionals to make informed decisions and provide appropriate care.&nbsp;</p><p><strong>2. Low sample concentration and User-friendly</strong></p><p>The GBS PCR and SMN1 genetic test kits offer the advantage of low sample concentration requirements. This means that even with limited sample volumes, accurate testing can still be performed. These kits are also highly user-friendly. Each package has clear and intuitive instructions that guide lab technicians through testing.</p><p><strong>3. High precision and Sensitivity</strong></p><p>Precision and sensitivity are crucial aspects of genetic testing; these gene detection kits excel in these areas. By employing state-of-the-art technology and stringent quality control measures, these kits provide exceptional sensitivity, enabling the detection of even low levels of target genetic material.&nbsp;</p><p><strong>4. More accessible: CE and NMPA marked</strong></p><p>Tianlong&#39;s commitment to quality and compliance is reflected in the CE and NMPA marks obtained for their gene detection kits. These certifications signify compliance with international quality standards and regulatory requirements.&nbsp;</p><p>*It is important to note that while the GBS test results provide a clinical reference, they cannot be solely relied upon as the basis for diagnosis or exclusion of cases. Therefore, healthcare professionals should interpret the results in conjunction with other clinical findings and follow established guidelines for patient management.&nbsp;</p><p><strong>Conclusion</strong></p><p>Tianlong is a tested and trusted provider of advanced gene detection solutions. Our company prioritizes research and development to constantly advance genetic testing. We provide healthcare professionals worldwide with innovative solutions that cater to their evolving needs.</p><p>By choosing Tianlong, health workers gain access to state-of-the-art technologies and comprehensive support, ensuring accurate and reliable patient results.</p>"
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